Pinpoint Pupils Pinpoint pupils (very tiny, constricted pupils) are one of the earliest and most recognizable signs of opioid overdose. When fentanyl affects the central nervous system, it forces the pupils to tighten dramatically, even in low light.
Extreme drowsiness / “nodding off” People may appear unusually sleepy, drift in and out of consciousness, or be unable to stay awake. Their responses may be slow or confused. This is caused by fentanyl suppressing brain activity and reducing oxygen levels.
Cold, clammy skin As breathing slows, blood flow and oxygen drop. The skin may feel cool, sweaty, or moist to the touch. This change often appears early and can worsen quickly if the person does not receive help.
Limp or very weak body Muscles lose strength when fentanyl depresses the nervous system. A person may be unable to sit up, control their movements, or keep their head from falling forward.
Nausea or vomiting Opioids can disrupt normal digestive function. Nausea or vomiting may occur suddenly, and if a person is very weakened or unconscious, vomiting increases the risk of choking.
Breathing slow, irregular, or stopped Fentanyl can severely suppress the part of the brain that controls breathing. Someone may take shallow breaths, breathe irregularly, or stop breathing entirely. This is the most dangerous sign and requires immediate emergency action.
Blue/gray lips or fingertips When oxygen levels drop, blood cannot circulate normally. Lips, nails, or fingertips may turn blue or gray — a sign of critical oxygen loss that indicates the person is not getting enough air.
Unresponsive or unconscious A person may not wake up even when shaken or called by name. Loud noises or pain may not get a response. This happens when fentanyl overwhelms the brain’s ability to stay awake.
Choking, gurgling, or loud snoring These sounds can indicate that the airway is partially blocked or that breathing is dangerously shallow. Gurgling or “death rattle” sounds mean the person’s airway needs to be cleared and emergency help is needed right away.
Slow or no heartbeat A weakening or absent pulse is a sign that the body is shutting down due to lack of oxygen. This is a life-threatening emergency and requires immediate CPR and naloxone if available.
How to Access Narcan Narcan is now on all Fresno County junior high and high school campuses due to a partnership between the Fresno County Department of Public Health and the Fresno County Superintendent of Schools. Get Narcan The public can access free Narcan from the following locations: Community Regional Medical Center San Joaquin Valley Needle Exchange Fentanyl Anonymous Mothers in Grief Support Group In addition, pharmacies sell it over the counter and the City of Fresno also requires businesses serving alcohol to have Narcan readily available.
How to Access Narcan Narcan is now on all Fresno County junior high and high school campuses due to a partnership between the Fresno County Department of Public Health and the Fresno County Superintendent of Schools. Get Narcan The public can access free Narcan from the following locations: Community Regional Medical Center San Joaquin Valley Needle Exchange Fentanyl Anonymous Mothers in Grief Support Group In addition, pharmacies sell it over the counter and the City of Fresno also requires businesses serving alcohol to have Narcan readily available.